San Francisco 49ers face potential setback as rookie wide receiver De'Zhaun Stribling, their top draft selection, suffered an ankle injury during the team's Week 1 victory against the Los Angeles Rams. Medical evaluations suggest the promising prospect may require surgical intervention to address the damage sustained during the game. This development could significantly impact the 49ers' offensive depth and Stribling's rookie season trajectory as the team assesses recovery timelines and roster adjustments.

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