Visualization of the first contact between the earliest reported human coronavirus and its human receptor molecule
- Posted on March 7, 2025
- By Bing News
- 1 Views
Visualization of the first contact between the earliest reported human coronavirus and its human receptor molecule
Coronavirus 229E is the earliest reported human coronavirus (hCoV-229E). Researchers used cryo-EM, glycoproteomics, and modeling to generate the atomic structure of a fully glycosylated and membrane-bound hCoV-229E spike protein bound to its host receptor, human aminopeptidase N (hAPN).
