Penn-made AI tool matched a patient’s rare disease with a common inflammation drug. He’s been in remission for over two years.

Doctors were preparing the patient for hospice, having tried every available treatment for his rare lymph node disorder, Castleman disease, which causes extreme swelling that can lead to organ failure. In a last-ditch effort, a Penn Medicine immunologist ran the patient’s medical history and lab work through an artificial intelligence tool that matches rare diseases with existing medications. ...