Stealth switch in tuberculosis enzyme could open route to drug-resistant treatment
- Posted on May 1, 2026
- By Bing News
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Stealth switch in tuberculosis enzyme could open route to drug-resistant treatment
Recent research published in Communications Biology marks an advance in structural biology by enhancing understanding of protein regulation mechanisms in Mycobacterium tuberculosis (Mtb), a global health threat. The team led by the University of Melbourne combined several advanced techniques at the Australian Synchrotron and the National Deuteration Facility to reveal the hidden allosteric mechanism that activates a key enzyme, ICL2.
